Tag: maralixibat

Pruritus in Cholestasis: Bile Acid Resins and New Treatment Options

Pruritus in Cholestasis: Bile Acid Resins and New Treatment Options

Cholestatic pruritus causes severe, persistent itching due to bile buildup. First-line treatment is cholestyramine, but newer options like maralixibat and rifampin offer better efficacy and tolerability. Antihistamines don't work-targeted therapies are changing outcomes.