Tag: anticholinergic burden

Anticholinergic Burden of Tricyclic Antidepressants: Cognitive and Cardiac Risks Explained

Anticholinergic Burden of Tricyclic Antidepressants: Cognitive and Cardiac Risks Explained

Tricyclic antidepressants like amitriptyline carry high anticholinergic burden, increasing risks of dementia and dangerous heart rhythms. Safer alternatives exist, and deprescribing can reverse cognitive decline.

Cumulative Anticholinergic Burden: How Antihistamines Combine with Other Medications to Risk Cognitive Decline

Cumulative Anticholinergic Burden: How Antihistamines Combine with Other Medications to Risk Cognitive Decline

First-generation antihistamines like Benadryl can significantly increase dementia risk when combined with other medications. Learn how cumulative anticholinergic burden affects older adults and what safer alternatives exist.